Aging Skin: GreenMedInfo.com’s Top 20 Longevity Promoting Substances

As concerns about accelerated skin aging continue to rise, groundbreaking research has unveiled the power of natural compounds to slow down and even reverse the visible signs of aging.

As we age, our skin undergoes a variety of changes that can lead to wrinkles, sagging, and a loss of radiance. While these changes are a natural part of the aging process, many people are seeking ways to slow down or even reverse the visible signs of aging. In recent years, there has been a growing interest in natural approaches to skincare, with many people turning to plant-based ingredients and therapeutic practices to help maintain a youthful appearance.

GreenMedInfo.com, the internet’s largest open-access natural health database, has compiled a wealth of research on natural interventions for aging skin. The database includes 262 unique study abstracts on substances and practices that may help to mitigate or reverse the effects of skin aging. In this report, we will highlight the 20 most compelling natural compounds and therapeutic actions identified by GreenMedInfo.com, and explore their potential implications for preventing and reversing skin aging.

GreenMedInfo’s Top 20 Natural Compounds and Therapeutic Actions for Skin Aging

1. Astaxanthin: This potent carotenoid has been the subject of five studies in the GreenMedInfo.com database. Research suggests that astaxanthin has strong antioxidative and photoprotective properties that may help to prevent UV-induced skin damage and aging.

2. Aloe vera: Two studies have found that topical aloe gel can significantly improve wrinkles, elasticity, and collagen production in photoaged skin.

3. Soy isoflavones: Four studies have investigated the effects of oral and topical soy isoflavones, such as genistein, on skin aging. The research suggests that these compounds may improve skin elasticity, hydration, and wrinkles, particularly in postmenopausal women.

4. Vitamin C: Seven studies have explored the potential of vitamin C, both topically and orally, for combating skin aging. When used in combination with other nutrients, vitamin C appears to have potent antioxidant and anti-aging effects on the skin.

5. Polyphenols: Six studies have investigated the effects of polyphenol-rich extracts from plants like hawthorn, artichoke, and grapes on skin aging. The research suggests that these compounds may have anti-inflammatory, antioxidant, and anti-aging benefits for the skin.

6. Rosemary extract: Three studies have found that rosemary extract may protect against UV damage and have antioxidant activity in skin cells.

7. Pomegranate: Seven studies have explored the potential of pomegranate extracts for combating skin aging. The research suggests that ellagic acid and other compounds in pomegranate may inhibit UV-induced inflammation, oxidative stress, and signs of skin aging.

8. Melatonin: Four studies have investigated the effects of topical melatonin on skin aging. The research suggests that melatonin may improve clinical signs of skin aging and protect against UV damage.

9. Vitamin E: Five studies have explored the potential of vitamin E, a lipid-soluble antioxidant, for combating skin aging. The research suggests that vitamin E may be effective both alone and in synergistic combinations with other nutrients.

10. Sulforaphane: Five studies have investigated the effects of sulforaphane, a compound found in broccoli sprouts, on skin aging. The research suggests that sulforaphane may protect skin against UV-induced oxidative damage and photoaging.

11. Coenzyme Q10: Two human studies have found that CoQ10 supplementation may improve wrinkles and skin microrelief.

12. Pycnogenol (pine bark extract): Two studies have explored the potential of oral and topical pine bark extract for improving visible signs of skin aging.

13. Resveratrol: Five studies have investigated the effects of resveratrol, a polyphenol found in grapes and red wine, on skin aging. The research suggests that resveratrol may have photoprotective, antioxidant, and anti-inflammatory properties in the skin.

14. Green tea polyphenols: Six studies have explored the potential of green tea compounds, such as EGCG, for protecting against photodamage and improving skin elasticity and wrinkles.

15. Sunlight exposure: While excessive UV exposure can be damaging to the skin, 15 studies in the GreenMedInfo.com database suggest that many plant extracts and nutrients may be photoprotective and beneficial for combating photoaging when combined with moderate sun exposure.

16. Red light therapy: Three studies have investigated the effects of red and near-infrared light on skin aging. The research suggests that these wavelengths of light may be effective for improving wrinkles, roughness, and other signs of skin aging.

17. Fermented foods and herbs: Four studies have explored the potential of compounds found in fermented foods and herbs, such as natto, kimchi, and fermented herb extracts, for stimulating collagen production and alleviating skin aging.

18. Probiotics: One study has investigated the effects of probiotics and prebiotics, such as Bifidobacterium longum and galacto-oligosaccharides, on skin aging. The research suggests that these compounds may help to protect skin from photoaging.

19. Ginseng: Four studies have explored the potential of topical ginseng extract, particularly red ginseng, for improving facial wrinkles and increasing procollagen synthesis in human skin.

20. Botanical extracts: Numerous studies in the GreenMedInfo.com database have investigated the potential of various plant extracts for combating skin aging. Some of the most promising extracts include chrysanthemum, rose, white mulberry, lotus, and saffron.

Implications for Natural Skincare and Healing

The research compiled by GreenMedInfo.com suggests that there are many natural compounds and therapeutic practices that may be effective for preventing and reversing skin aging. These findings have important implications for those seeking to maintain a youthful appearance without relying on synthetic or invasive treatments.

One key takeaway from the research is the importance of antioxidants in combating skin aging. Many of the top compounds identified by GreenMedInfo.com, such as astaxanthin, vitamin C, polyphenols, and green tea extract, are potent antioxidants that can help to protect the skin from oxidative stress and damage. Incorporating these compounds into a skincare routine, either topically or orally, may help to prevent the development of wrinkles, sagging, and other signs of aging.

Another important finding is the potential of certain compounds to protect against UV damage and photoaging. While excessive sun exposure is a major contributor to skin aging, the research suggests that many natural compounds, such as pomegranate extract, sulforaphane, and resveratrol, may help to mitigate the damaging effects of UV radiation. Incorporating these compounds into a skincare routine, along with appropriate sun protection measures, may help to prevent photoaging and maintain a youthful appearance.

The research also highlights the potential of certain therapeutic practices, such as red light therapy and moderate sun exposure, for combating skin aging. While more research is needed to fully understand the mechanisms behind these practices, the findings suggest that they may be effective complementary approaches to traditional skincare.

Finally, the research compiled by GreenMedInfo.com underscores the importance of a holistic approach to skincare and anti-aging. Many of the top compounds and practices identified in the database work synergistically to promote healthy, youthful-looking skin. By incorporating a variety of natural compounds and therapeutic practices into a comprehensive skincare routine, individuals may be able to achieve optimal results and maintain a radiant, ageless appearance.

The entire database of studies in natural approaches to address Skin Aging can be downloaded in PDF as a professional (GMI PRO) member. You can get access to a library of over 100,000 research PDFs, valued in total at over $250,000 when you enroll as a professional user. Learn more about becoming a member here.

Source: Aging Skin: GreenMedInfo.com’s Top 20 Longevity Promoting Substances